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ME Bio offers highly purified, standardized Seallagen-MCT (technical grade echinoderm collagen) matrices with unique properties for expansion of medical technologies and the progress of novel cell-based therapies. Isolated from echinoderm mutable collagenous tissue (MCT) known by its unique collagen composition, Seallagen-MCT shows excellent biocompatibility and safety, due to key biological properties, such as biodegradability and low antigenicity, eliminating the risk of serious disease transmission. Our Seallagen-MCT membranes and fibrillar suspensions open up a range of applications for R&D, such as:
Trust the ME Bio’s highly purified collagen products and experience improved research productivity allowing security of product consistency and reproducible results.
Echinoderms possess a unique connective tissue (Mutable Collagenous Tissue, MCT). Echinoderm MCT is composed of collagen fibrils interconnected by glycosaminoglycans, the major components of neodermis, creating the optimal environment for collagen biosynthesis, showing improved biocompatibility, biodegradability, and safety. Echinoderm MCT unique physical, chemical, and biological properties allow fabrication of stable hydrogels thorough fibrogenesis. It also constitutes a suitable polymeric matrix for electrospinning, 3D-bioprinting, and biocompatible nanocoating and cell culture. Seallagen-MCT products are best suited for the cultivation of adherent primary cells, stem cells, and cell lines. The unique properties of Seallagen-MCT matrix make it an ideal tool for implantation of cell-matrix complexes, their analysis by fluorescence imaging and histological preparation.